43. Jessica Lange (Born In 1949) – Tootsie, American Horror Story

Jessica Lange's first big movie was King Kong in 1976. She went on to win Oscars for Tootsie and Blue Sky, and later earned Emmys for American Horror Story and Grey Gardens.

She has kept challenging herself onstage too. She won a Tony for Long Day's Journey Into Night at 67 and returned to Broadway in 2024 with Mother Play, which brought her another Tony nomination.