33. Oprah Winfrey (Born In 1954) – The Oprah Winfrey Show

Oprah Winfrey's talk show ran for 25 seasons and made her one of the most influential people in the world. She also earned an Oscar nomination for her first film role, in The Color Purple.

Now in her 70s, she's as busy as ever. She produces films and series, runs her famous book club, and has talked openly about her health and weight journey, encouraging fans to take care of themselves at any age.