Kathy Bates won an Oscar for her terrifying turn in Misery and went on to shine in Titanic, Fried Green Tomatoes and American Horror Story. She has also survived both ovarian and breast cancer.
In her mid-70s, she took on her first leading role on network TV in CBS's Matlock, which became a hit and earned her an Emmy nomination. She has also talked openly about losing around 100 pounds to protect her health.
